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탄탄한 실력과 전문성을 갖춘 열정적인 교수진

강희규 교수

강희규 교수

전공 :
분자발생학 
전화 :
031-740-7303 
연구실 :
지천관 B108 
E-mail :
kanghg@eulji.ac.kr

학력

  • 한양대학교 생물학과 졸업 (‘89)이학사
    한양대학교 생물학과 졸업 (‘92)이학석사
    한양대학교 생물학과 졸업 (‘00)이학박사
  • 주요경력

  • 現을지대학교임상병리학과교수
    前(2001~2015)보건과학연구소연구소장
    前(2013~2017.07)연구지원센터장
    現(2017.08~현재)산학협력단장, 성남고령친화종합체험관단장

  • 연구실적

  • [논문]
    [1] Quantitative Assessment of Ischemic Tissue Damage in Ovarian Cortical Tissue With or Without Antioxidant (Ascorbic Acid) Treatment. Fertil Steril, 2004, 82, 679-85.
    [2] Assessment of the Integrity of Human Oocytes Retrieved From Cryopreserved Ovarian Tissue After Xenotransplantation. Hum Reprod, 2005, 20, 2502-8.
    [3] Anodically nanostructured titanium oxides for implant applications. Electrochimica Acta, 2008, 53, 4846-4851.
    [4] Colorimetric detection of ssDNA in a solution. Current Applied Physics, 2009, 9, 534-537.
    [5] Surfactant-free preparation of ZnO dendritic structures by electrochemical method. Current Applied Physics, 2010, 10, 740-743.
    [6] Electrochemical Immunosensor Using a Gas Diffusion Layer as an Immobilization Matrix. Bulletin of the Korean Chemical Society, 2011, 32, 1975-1979.
    [7] Effect of Spirulina maxima on spermatogenesis and steroidogenesis in streptozotocin-induced type I diabetic male rats, Food Chemistry, 2012, 134, 173-179.
    [8] Inhibition of Androgen Receptor Expression With Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells. Scientific World Journal, 2013, 2013, 519397.
    [9] Establishment of Validation Methods to Test the Biocompatibility of Titanium Dioxide. Bulletin of the Korean Chemical Society, 2013, 34, 1857-1863.
    [10] Effects of Coculture With Immune Cells on the Developmental Competence of Mouse Preimplantation Embryos in Vitro and in Utero. Reprod Sci, 2015, 22, 1252-61.
    [11] Proteomic Analysis of Serum From Patients With Major Depressive Disorder to Compare Their Depressive and Remission Statuses. Psychiatry Investig, 2015, 12, 249-59.
    [12] Reconsidering azobenzene as a component of small-molecule hypoxia-mediated cancer drugs: A theranostic case study. Biomaterials, 2017, 115, 104-114.
    [13] Spirulina Extract Enhanced a Protective Effect in Type1 Diabetes by Anti-Apoptosis and Anti-ROS Production. Nutrients. 2017, 9.
    [14] Identification and Validation of SAA4 as a Rheumatoid Arthritis Prescreening Marker by Liquid Chromatography Tandem-mass Spectrometry. Molecules. 2017, 22.
    [15] N-glycoproteomic analysis of human follicular fluid during natural and stimulated cycles in patients undergoing in vitro fertilization. Clin Exp Reprod. Med, 2017, 44, 63-72.
    [16] Identification of Transcription Factor YY1 as a Regulator of a Prostate Cancer-Specific Pathway Using Proteomic Analysis. J Cancer. 2017, 8, 2303-2311
    [17] Extracellular vesicles from KSHV-infected endothelial cells activate the complement system. Oncotarget. 2017, 8, 99841-99860.
    [18] Proteomics analysis reveals differential pattern of widespread protein expression and novel role of histidine-rich glycoprotein and lipopolysaccharide-binding protein in rheumatoid arthritis. International Journal of Biological Macromolecules. 2018, 109, 704–710.
    [19] Bicalutamide enhances fodrin-mediated apoptosis through calpain in LNCaP. Experimental Biology and Medicine 2018, 243, 843–851.
    [20] Development of the WISH (Well-Aging Indexing for Senior Health) Platform for Happiness. J. Open Innov. Technol. Mark. Complex. 2018, 4, 36.
    [21] The relationship between morningness-eveningness and resilience in mood disorder patients. Comprehensive Psychiatry.2018, 87, 72–78.
    [22] Estimation of Age of Bloodstains by Mass-Spectrometry: A Metabolomic Approach. Anal Chem. 2018, 90, 12431-12441.
    [23] Development of a Novel Diagnostic Biomarker Set for Rheumatoid Arthritis Using a Proteomics Approach. Biomed Res Int. 2018, 26; 2018:7490723.
    [24] Genetic association study of CSNK1E gene in bipolar disorder and circadian characteristics. Nord J Psychiatry. 2018, 72, 599-604.
    [25] Estimation of Age of Bloodstains by Mass-Spectrometry: A Metabolomic Approach. Anal Chem. 2018, 6; 90, 12431-12441.
    [26]. Proteomics Analysis for Verification of Rheumatoid Arthritis Biomarker Candidates Using Multiple Reaction Monitoring. Proteomics Clin. Appl. 2019, 13, e1800011.
    [27] A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression. Chem Commun (Camb). 2019, 55, 537-540.
    [28] An automated high-throughput sample preparation method using double-filtration for serum metabolite LC-MS analysis. Analytical Methods. 2019, 11, 4060-4065.
    [29] Influence of swabbing solution and swab type on DNA recovery from rigid environmental surfaces. J Microbiol Methods. 2019, 161, 12-17.
    [30] Mass Spectrometry-based Comparative Analysis of Membrane Protein: High-speed Centrifuge Method Versus Reagent-based Method. Korean J Clin Lab Sci. 2019, 51, 78-85.
    [31] Influence of Tacrolimus on Depressive-Like Behavior in Diabetic Rats Through Brain-Derived Neurotrophic Factor Regulation in the Hippocampus. Neurotox Res. 2019, 36, 396-410.
    [32] Internal standard metabolites for obtaining absolute quantitative information on the components of bloodstains by standardization of samples. Forensic Science International 2019, 294, 69–75.
    [33] Proteomics Approach for the Discovery of Rheumatoid Arthritis Biomarkers Using Mass Spectrometry. Int. J Mol Sci. 2019, 5, 210-228.
    [34] Presoaking dried blood spot with water improves efficiency for small-molecule analysis. Biotechniques. 2019, 67, 219-228.
    [35] Comparison of Swabbing Solution Volume and gDNA Extraction Kits on DNA Recovery from Rigid Surface. Indian J Microbiol, 2020, 60(2):206-213.
    [36] Metabolomic profiling of bloodstains on various absorbent and non-absorbent surfaces. Anal. and Bio. Chem. 2020, doi.org/10.1007/s00216-019-02371-3.
    [37] DNA and Protein Analysis from Dried Blood Spot Using Tris-EDTA and Phosphate Buffered Saline. TEST2020, 83, 13222-13227.
    [38] Proteomics-Based Identification of Diagnostic Biomarkers Related to Risk Factors and Pathogenesis of Ischemic Stroke. Diagnostics 2020, 10, 340; doi:10.3390/diagnostics10050340.
    [39] Proteomics Reveals Plasma Biomarkers for Ischemic Stroke Related to the Coagulation Cascade. Journal of Molecular Neuroscience. doi.org /10.1007/s12031-020-01545-4.
    [40] Spatiotemporal expression of aquaporin 9 is critical for the antral growth of mouse ovarian follicles. Biology of Reproduction, 2020, 1–12.
    [41] A discovery of screening markers for rheumatoid arthritis by liquid chromatography mass spectrometry: A metabolomic approach. Int J Rheum Dis. 2020;00:1–10.
    [42] Development of novel extraction reagents for analyzing dried blood spots from crime scenes. Forensic Science International. 2020, 317, 110531.
    [43] Association between Altered Blood Parameters and Gut Microbiota after Synbiotic Intake in Healthy, Elderly Korean Women. Nutrients 2020, 12, 3112; doi:10.3390/nu12103112.
    [45] Fluorescent Probe for Monitoring Hydrogen Peroxide in COX-2-Positive Cancer Cells. ACS Appl. Bio Mater. 2020. dx.doi.org/10.1021/acsabm.0c01135
    [46] Serum biomarker panel for the diagnosis of rheumatoid arthritis. Arthritis Research
  • 연구분야

  • [1] 오믹스분석 질환마커개발을 위한 임상연구
    - 오믹스 기반 단백체 분석을 통해서 우울증/류마티스관절염/뇌졸중/심근경색등의 질환 바이오 마커 발굴 연구.
    - 발굴 된 질환바이오마커의 임상적용을 위한 유효성 검증 연구.
    [2] 혈액 성분 변화를 활용한 혈흔 유류경과시간 분석 기법 개발
    - 방치 시간 별 혈흔을 분석하여 혈흔유류경과시간을 추정할 수 있는 대사체 마커를 발굴.
    - 유류경과시간 지표 대사체 마커 발굴과 함께 현장 적용에 초점을 맞춘 연구 진행.
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